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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Stem Cells Dev. 2010 Nov 9;20(6):1021–1029. doi: 10.1089/scd.2010.0198

Figure 4. SDF-1 knockdown diminishes the protective effect of CdM.

Figure 4

A, B) mNPC survival was significantly reduced after 48 hrs of hypoxic culture when treated with shSDF-1 CdM compared with shScram CdM. C) Addition of recombinant SDF-1 to alpha MEM containing 20ug/ml heparin increased mNPC survival in a dose-response manner: 0.5 ng/ml SDF-1: 18.3 ± 5.9% increase, P = 0.022; 1 ng/ml SDF-1: 26.7 ± 8.8% increase, P = 0.016. N.S., not significant; *P ≤ 0.05; **P ≤ 0.01; †P ≤ 0.01. GM, NSC growth medium. SFM, serum-free alpha MEM (base medium).