Table 2.
Electrophysiology of SMG neurons in mice injected with rabbit IgG
Control | EAAN (days 2 and 3) | Recovered (day 27) | |
---|---|---|---|
Spontaneous f-EPSPs | 30/30 | 17/34 | 15/15 |
Evoked f-EPSPsa | 30/30 | 17/34 | 15/15 |
Evoked s-EPSPa | 19/30 | 21/34b | 11/15 |
Spontaneous f-EPSP frequency (min−1) | 197.5 ± 50.5 (30) | 33.2 ± 7.7 (17)* | 380.5 ± 55.0 (15)* |
Evoked f-EPSP frequency (min−1)b | 576.6 ± 93.8 (30) | 173.5 ± 38.5 (17)* | 1020.9 ± 92.1 (15)* |
Amplitude of evoked s-EPSPs (mV)b | 2.5 ± 0.3 (19) | 2.8 ± 0.4 (21) | 3.5 ± 0.5 (11) |
Data are expressed as neurons responding per number tested, or as mean ± SEM (number of cells analyzed).
p < 0.05 compared with control (t test).
Responses evoked by colonic distention.
Ten neurons exhibited s-EPSPs but no f-EPSPs in response to colonic distention. The difference in number of s-EPSP responses compared with control mice was not statistically significant.