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. Author manuscript; available in PMC: 2011 Jul 5.
Published in final edited form as: J Neurosci. 2011 Jan 5;31(1):78–88. doi: 10.1523/JNEUROSCI.3542-10.2011

Figure 9. Neurotransmitter expansion in the VSC and spinal cord of activity-manipulated larvae.

Figure 9

A. The number of TH neurons in the VSC core and annulus increases upon overexpression of rNav2a αβ. Expansion of the TH phenotype occurs within the Lim1,2 population in both core and annulus (**p<0.01, ***p<0.001, compared to control by the Mann-Whitney U test), and the expansion in the annulus is significantly greater than the expansion in the core (*p<0.05, comparing normalized control to rNav2a αβ values for the core and annulus with the Kruskal-Wallis test followed by the Conover post-hoc analysis). Stage 42; values are mean ± SEM for n=6 embryos. B. rNav2a αβ overexpression expands the TH phenotype within the ventral GABA+ population of the spinal cord (*p<0.05, comparing control versus rNav2a αβ values by the Mann-Whitney U test), increasing the number of clusters of TH+/GABA+ cells (*p<0.05, comparing control versus rNav2a αβ values by the Mann-Whitney U test). Stage 35; values are mean ± SEM for n≥4 larvae.