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. Author manuscript; available in PMC: 2011 Jan 25.
Published in final edited form as: Viruses. 2010;2(9):2000–2012. doi: 10.3390/v2092000

Figure 1.

Figure 1

MMTV infection. MMTV binds to TfR1 on the cell surface and is internalized into a low pH compartment. After uncoating, the viral genome is reverse-transcribed, is transported to the nucleus, and the provirus integrates into the genome. At least five different RNAs are transcribed from the integrated provirus (see text). The Env membrane proteins are synthesis in the rough endoplasmic reticulum (RER) and traffic through the Golgi network (GN). Little is known about MMTV virion assembly, although it occurs in an intra-cellular compartment. Abbreviations: E, endosome; EE, early endosome; LE, late endosome.