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. Author manuscript; available in PMC: 2011 Sep 9.
Published in final edited form as: J Neurosci. 2011 Mar 9;31(10):3670–3682. doi: 10.1523/JNEUROSCI.4750-10.2011

Figure 7. Single rod and ERG-derived responses to half-saturating flashes exhibit similar kinetics across conditions.

Figure 7

A) The time-to-peak of the half-saturating response (y-axis) for single rod recordings plotted against time-to-peak of the single photon response (x-axis). B) Population mean normalized half-saturating outer segment current responses in L-15/Locke’s, Ames’Ca,Mg/Ames’Ca,Mg, and Ames’/Ames’, and the normalized single photon response in L-15/Locke’s and Ames’/Ames’ (red and black dashed lines, see Fig. 4). C) ERGs in response to increasing delays between test (27Rh*) and probe (2400Rh*) flashes. D) Isolated ERG response to a flash producing 27Rh* in Ames’ and the normalized derived rod response using the paired-pulse technique to the same test flash strength. Smooth curve fit to the data is r(t) = γ[(1−exp(−α(t−td)2)] exp(−1/τ), td = −7.8ms, γ = 2.4, α = 2.3×10−4ms2, τω = 121ms. E) Average derived rod responses in Ames’/Ames’ (black, td = −4.1ms, γ = 1.7, α = 3.0×10−4ms2, τω = 134ms) and L-15/Locke’s (red, td = 0.56ms, γ = 1.7, α = 3.8×10−4ms2, τω = 191ms). The grey dashed line is the same model using the in vivo ERG-derived parameters {Hetling 1999}, (td = 3.1ms, γ = 1.84, α = 3.23×10−4ms2, τω = 163ms). The dashed lines plots the normalized single photon response in L-15/Locke’s and Ames’/Ames’ (red and black dashed lines, see Fig. 4).