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. Author manuscript; available in PMC: 2012 Oct 18.
Published in final edited form as: Cancers (Basel). 2010 May 4;2(2):773–793. doi: 10.3390/cancers2020773

Figure 6.

Figure 6

Melanocytes activation following subcutaneous injection of 1.0 mg α-gal glycolipids into the KO mouse. A. The epidermis displays 4–5 layers of cells 7 days post injection in the black spot area. The apical region under the keratinous layer (stained in red) is filled with many melanin granules. B. The injected skin four weeks post injection. The epidermis displays normal structure of ~2 layers of epidermal cells, the amount of melanin granules is residual and the overall color of the skin returns to normal pink (×400).