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. Author manuscript; available in PMC: 2011 Sep 23.
Published in final edited form as: J Neurosci. 2011 Mar 23;31(12):4755–4764. doi: 10.1523/JNEUROSCI.6594-10.2011

Figure 6.

Figure 6

U0126 increases synaptophluorin response in an L type calcium channel dependent manner. (i) Experimental scheme for drug treatment. Pink vertical bars indicate times of imaging. (ii – iii) Lines connect dF in individual boutons (ii) and average response from individual cells (iii) at the 6th second of electrical stimulaton. Colors of lines represent individual cells (iii). (iv) Dynamics of dF before (0 – 6 seconds) and during (6 – 12 seconds) stimulation. Insets show dF over 68 seconds including fluorescence decay after stimulation (12–68 seconds). Rectangular box corresponds to the time window shown in the main diagram. Data points are separated by 1 second. Horizontal bar on top of the graphs show duration of electrical stimulation. Number of cells/boutons is shown in parentheses. Data are presented as means ± S.E.M. * p<0.05, ** p<0.01 compared to corresponding values obtained with DMSO.