Skip to main content
. Author manuscript; available in PMC: 2011 Sep 30.
Published in final edited form as: J Neurosci. 2011 Mar 30;31(13):4886–4895. doi: 10.1523/JNEUROSCI.5122-10.2011

Figure 7. Exocytosis in Otof−/− hippocampal neurons.

Figure 7

A, representative EPSC traces from Otof+/+ (black) and Otof−/− (grey) autaptic hippocampal neurons at 10 to 15 DIV, elicited by depolarizations to 0 mV for 2 ms at 0.2 Hz.

B, mean normalized amplitudes of EPSCs during a train of action potentials at 10 Hz from Otof+/+ and Otof−/− hippocampal neurons.

C, representative traces showing the release of the readily releasable pool (RRP) induced by application of 0.5 M sucrose.

D, representative traces of miniature EPSC (mEPSCs) in the presence of 300 nM TTX at −70 mV. The frequency and the amplitude of mEPSCs was unchanged in Otof−/− neurons.