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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Cell Death Differ. 2011 Feb 25;18(8):1366–1375. doi: 10.1038/cdd.2011.12

Figure 8.

Figure 8

Accumulation of p53 in the epithelial cells of the lens from hauspFL/FL; nes-cre knockout mice. HAUSP staining was detected in the epithelial cells of the lens (a; arrows) and surrounding cells from the hauspFL/FL mice, which was missing in the epithelial cells of lens (b; arrowheads), but not in the surrounding cells from the hauspFL/FL; nes-cre mice, because of ectopic expression of nes-cre in the epithelial cells of mouse lens. The stabilization of p53 was detected in the epithelial cells of lens from the hauspFL/FL; nes-cre mice (d; arrowheads), but not in the epithelial cells of lens from the control mice (c; arrows). The higher magnified pictures of the insects showed nuclear staining of accumulated p53 protein in the epithelial cells of the lens from the hauspFL/FL; nes-cre mice (f; arrowheads), but not in the epithelial cells of the lens from the control mice (e; arrows)