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. Author manuscript; available in PMC: 2013 Mar 13.
Published in final edited form as: J Neurosci. 2011 Apr 13;31(15):5648–5658. doi: 10.1523/JNEUROSCI.3452-10.2011

Figure 3. AKAP inhibitory peptide inhibits reinstated cocaine seeking but not locomotor activity.

Figure 3

A, Active lever presses for animals used in studying the behavioral effects of St-Ht31 peptide on reinstatement of cocaine seeking. B, Microinjection of St-Ht31 peptide significantly impaired reinstatement compared to microinjection of St-Ht31P. Active lever presses are shown as total presses over a 2 hr reinstatement trial. C, Lack of effect by St-Ht31 on distance traveled in response to an acute cocaine challenge (10 mg/kg, i.p.). *p≤ 0.05, comparing control to active peptide using a two-tailed Student's paired t-test.