Scheme 10.
a(i) HNO3, H2SO4, CH2Cl2, 74% (ii) con. HCl, 95 °C (iii) MeOH, SOCl2, 60 °C, 72% (2 steps) (iv) NEt3, CH2Cl2, 97% (v) LiOH, H2O, THF (vi) (PhO)2P(O)N3, NEt3, PhMe, 90 °C, 86% (2 steps) (vii) pyBOP, NEt3, CH2Cl2, 74%
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