A, Six hours after extinction training, infusion of the p300 inhibitor C646 (EXT, 1.5 μg, n = 7), directly into the infralimbic prefrontal cortex (ILPFC), has no effect on the formation of fear extinction memory. B, An immediate postextinction training infusion of the p300 inhibitor C646 (EXT, 1.5 μg, n = 7), directly into the prelimbic prefrontal cortex (PLPFC), has no effect on the formation of fear extinction memory.