Table 1.
Mouse strains | 1.85 log cd m−2 | 2.57 log cd m−2 | p2-value | RPE65 variant |
---|---|---|---|---|
Irbp+/+Tα−/− (n = 5) | 0.71 ± 0.01 | 0.80 ± 0.02 | 0.002 | |
Irbp−/−Tα−/− (n = 5) | 0.66 ± 0.02 | 0.69 ± 0.02 | 0.22 | Leu450 |
p1-value | 0.041 | 0.003 | ||
129S2/Sv (n = 5) | 0.74 ± 0.01 | 0.78 ± 0.01 | 0.04 | |
Irbp−/− [129S2/Sv] (n = 5) | 0.66 ± 0.03 | 0.69 ± 0.02 | 0.41 | Leu450 |
p1-value | 0.019 | 0.007 | ||
C57Bl/6 (n = 5) | 0.74 ± 0.02 | 0.82 ± 0.02 | 0.02 | |
Irbp−/− [C57Bl/6] (n = 3) | 0.71 ± 0.03 | 0.78 ± 0.02 | 0.15 | Met450 |
p1-value | 0.50 | 0.24 |
Data were derived from mouse optomotor responses to rotating gratings under two photopic background illumination conditions (1.85 log cd m−2 or 2.57 log cd m−2). Values are means ± SEM. Significance levels: p1-values indicate comparisons between specified pairs of mouse strains (within the same background light intensity), and p2-values indicate comparisons within the same mouse strain (between two different illumination conditions).