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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: ACS Med Chem Lett. 2011;2(8):592–596. doi: 10.1021/ml2000824

Figure 2.

Figure 2

High-throughput screening results. A) Single-well positive controls containing DDAH (20 nM, ●) for all plates screened are compared with negative controls containing no enzyme (□). B) Mean percent inhibition of duplicates for all library compounds screened. The dashed line represents the cutoff for “hits” (50 %). C) Per-plate Z’ factors. D) Per-plate Z factors. See Supporting Information for details.