Figure 8.
Change in stem cell markers in K-ras activated mouse within 15 days after TAM treatment. Western blot for A) LGR5 or B) CD44 from the lysates of stomach from control or K-ras activated mice 13-16 days after TAM treatment. Immunofluorescence staining for CD44 in the forestomach of the C) control and D) K-ras activated mice, or in the glandular stomach (E and F), 15 days after TAM feeding. Immunofluorescence staining for Dcamkl1 in stomach of G) control and H) K-ras activated mice. Scale bar 200μM.