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. Author manuscript; available in PMC: 2012 Jan 13.
Published in final edited form as: J Neurosci. 2011 Jul 13;31(28):10347–10358. doi: 10.1523/JNEUROSCI.1470-11.2011

Figure 8.

Figure 8

Long-term effects of juvenile exposure to VEH, MPH, FLX, or MPH+FLX on protein phosphorylation within the VTA 2-months after the last injection (n= 8 per group). Exposure to MPH+FLX significantly increased the levels of phospho (p) ERK2 (A), p-CREB (B), and p-mTOR proteins (C) without affecting total (t) levels of protein when compared to the VEH-pretreated controls (p< 0.05, respectively). *Significantly different from the VEH-pretreated controls (p< 0.05). Data are presented as a ratio of total protein normalized to GAPDH (mean ± SEM).