Table 1.
Group | N | Treatment | Interval 1 | Test 1 | Interval 2 | Test 2 |
---|---|---|---|---|---|---|
1 | 78 | VEH, MPH, FLX, or MPH+FLX | 24-h | Conditioned place preference | X | X |
2 | 30 | VEH, MPH, FLX, or MPH+FLX | 24-h | Elevated plus-maze | 2-months | Forced swim test |
3 | 30 | VEH, MPH, FLX, or MPH+FLX | 24-h | Forced swim test | X | X |
4 | 32 | VEH, MPH, FLX, or MPH+FLX | 24-h | Polymerase chain reaction | X | X |
5 | 77 | VEH, MPH, FLX, or MPH+FLX | 2-months | Conditioned place preference | X | X |
6 | 40 | VEH, MPH, FLX, or MPH+FLX | 2-months | Sucrose Preference | 48 h | Elevated plus-maze |
7 | 32 | VEH, MPH, FLX, or MPH+FLX | 2-months | Polymerase chain reaction + Western Blot | X | X |
8 | 47 | VEH, MPH, FLX, or MPH+FLX | 2-months | Viral Surgery | 3 days | Forced swim test |
VEH: 0.9% sterile saline, MPH: methylphenidate (2.0 mg/kg), FLX: fluoxetine (2.5 mg/kg), MPH+FLX: methylphenidate and fluoxetine (2.0 and 2.5 mg/kg, respectively).