Table 1.

Characteristics of the studies included in the systematic review of the effects of oxalates on dentin hypersensitivity

	First author, year of publication
	Pamir, 2007	Gillam, 2004	Pillon, 2004	Camps, 2003	Pereira, 2001	Morris, 1999	Gillam, 1997	Holborow, 1994	Cuenin, 1991	Cooley, 1989	Muzzin, 1989	Hansson, 1987
Design	RCT	RCT, split mouth	RCT, split mouth	RCT, split mouth	RCT, split mouth	RCT, split mouth	RCT, split mouth	RCT, split mouth	RCT	RCT, split mouth	RCT, split mouth	RCT
Follow-up duration	4 wk	4 wk	3 wk	2–3 min	1 y	3 mon	3 mon	4 wk	Immediate	3 mon	4 wk	4 wk
Country	Turkey	England (UK)	Brazil	France	Brazil	United States	UK	New Zealand	United States	United States	United States	United States
Setting	University	University	University	University	University	Military	University	NR	Military	University	University	University
Funding	Manufacturers (products only)	Block Drug Co., Inc. (now GlaxoSmithKline)	None	University	CAPES	NR	None	J.O. Butler Co.	US Military, NIH	NR	Baylor University	NR
N of participants by group	15 / 15	13	15	87	19	10	10	30	6 / 7	28	17	14 / 14
N of teeth by group	15 / 15	13 / 13	15 / 15	87 / 87	23 / 21 / 24 / 14	10 / 10	11 / 33	30 / 30	6 / 7	28 / 28	17 / 17 / 17 / 17	mean 6 / 9.8 per patient
Age	18–57	Mean 46.2 (SD 4.2)	NR	Mean 32 (SD 11), 17–52	21–45	Mean 32.9, 21–43	Mean 45.1 (SD 8.8)	NR	Mean 45, 29–68	NR	Mean 40.5, 23–68	Mean 48, 23–61 Mean 51, 30–63
Gender (% female)	70	62	NR	72	58	50	60	NR	NR	NR	59	71 /79
Experimental Intervention	*3% monohydrogen-monopotassium oxalate gel, pH 2	*6.8% ferric oxalate in 0.9% saline	*3% monohydrogen-monopotassium oxalate gel, pH 4	*3% monohydrogen-monopotassium oxalate gel, pH 2	*3%, 6% monohydrogen-monopotassium oxalate gel, pH 4 + carboxymethyl cellulose *3% monohydrogen-monopotassium oxalate gel, pH 2.5 + carbopol	*Oxalate-containing pre-polymerized resin solution	*3% monohydrogen-monopotassium oxalate	*3% monohydrogen-monopotassium oxalate pH 2	*3% monohydrogen-monopotassium oxalate pH 2.4	*30% dipotassium oxalate pH 5.6 + 3% monohydrogen-monopotassium oxalate	*distilled water, then 30% dipotassium oxalate pH 5.6 *distilled water, then 3% monohydrogen-monopotassium oxalate pH 2 *30% dipotassium oxalate pH 5.6, then 3% monohydrogen-monopotassium oxalate pH 2	*30% dipotassium oxalate pH 5.6, then 3% monohydrogen-monopotassium oxalate pH 2
Control Intervention	placebo (distilled water)	placebo (undisclosed)	placebo (100 mg carbopol, 30 mg 1% green tincture, 30 mg blue tincture	placebo (4% glucose solution)	placebo (water + carboxymethyl cellulose	placebo (distilled water)	No treatment	placebo (water + non-staining dye)	placebo (3% sodium chloride, pH 2.4)	placebo (distilled water)	placebo (2 applications of distilled water	placebo (2 applications of distilled water)
Pain stimuli	Thermal, Evaporative	Thermal, Tactile, Evaporative	Routine activities of eating, drinking, and tooth cleaning	Tactile, Evaporative	Tactile, Evaporative	Tactile, Evaporative	Thermal, Tactile, Evaporative	Thermal, Tactile	Evaporative	Thermal	Thermal	Thermal, Routine Stimuli
Outcomes	*Pain visual analog scale (cm)	*Temperature eliciting pain (°C) *Force eliciting pain (g) *Pain visual analog scale (cm)	*Pain visual analog scale	*Force eliciting pain (cN) *Pain (+/−)	*Pain verbal rating scale	*Pain visual analog scale	*Temperature eliciting pain (°C) *Force eliciting pain (g) *Pain visual analog scale	*Pain scale	*Pain numeric rating scale	*Pain verbal rating scale	*Temperature eliciting pain (°C)	*Temperature eliciting pain (°C) *Pain visual analog scale *Pain verbal description scale *Pain numerical rating scale *McGill pain questionnaire
Adverse Events	None	None	None	None	None	NR	None	None	None	NR	None

RCT: Randomized clinical trial, SD: standard deviation, NR: Not reported