Appendix table.
Results of clinical studies on dentin hypersensitivity by stimuli and oxalate treatments.
| Experimental | Placebo | Standardized mean difference (95%CI) | |||||
|---|---|---|---|---|---|---|---|
| N | Mean | SD | N | Mean | SD | ||
|
3% monohydrogen monopotassium oxalate
| |||||||
| Pain elicited by routine stimuli | |||||||
| Gillam, 1997 | - | - | - | ||||
| Pillon, 2004 | 15 | −81.00 | 14.82 | 15 | −34.70 | 11.86 | −3.36 (−4.52; −2.20) |
| Pain elicited by thermal stimulus | −1.00 (−1.44; −0.56) | ||||||
| Gillam, 1997 | |||||||
| Holborow, 1994 | 30 | 1.00 | 1.00 | 30 | 2.27 | 1.75 | −0.88 (−1.41; −0.35) |
| Pamir, 2007 | 15 | 1.60 | 1.84 | 15 | 4.60 | 2.69 | −1.27 (−2.06; −0.47) |
| Pain elicited by tactile stimulus | 0.88 (0.21; 1.54) | ||||||
| Gillam, 1997 | - | - | - | ||||
| Holborow, 1994 | - | - | - | ||||
| Pereira, 2001 | 17 | 1.46 | 1.18 | 7 | 0.66 | 0.86 | 0.70 (−0.21; 1.61) |
| Pereira, 2001 | 14 | 1.38 | 0.50 | 7 | 0.66 | 0.86 | 1.09 (0.11; 2.06) |
| Pain elicited by evaporative stimulus | −0.27 (−0.81; 0.28) | ||||||
| Camps, 2003 | 87 | 0.38 | 0.49 | 87 | 0.70 | 0.46 | −0.68 (−0.98; −0.37) |
| Cuenin, 1991 | 6 | 1.50 | 1.05 | 7 | 0.57 | 0.79 | 0.94 (−0.23; 2.12) |
| Pamir, 2007 | 15 | 1.40 | 1.92 | 15 | 3.33 | 2.06 | −0.94 (−1.70; −0.18) |
| Pereira, 2001 | 15 | 0.53 | 0.64 | 8 | 0.55 | 1.13 | −0.02 (−0.88; 0.84) |
| Pereira, 2001 | 13 | 0.61 | 0.65 | 8 | 0.55 | 1.13 | 0.07 (−0.81; 0.95) |
| Temperature at which patient report pain (thermal stimulus) | |||||||
| Muzzin, 1989 | 17 | 3.35 | 2.35 | 17 | 3.76 | 3.59 | −0.13 (−0.81; 0.54) |
| Force at which patient report pain (tactile stimulus) | |||||||
| Camps, 2003 | 87 | −85.00 | 24.00 | 87 | −53.00 | 17.00 | −1.53 (−1.87; −1.19) |
|
| |||||||
|
3% monohydrogen monopotassium oxalate + 30% dipotassium oxalate
| |||||||
| Pain elicited by routine activities | |||||||
| Hansson, 1987 | 14 | 11.49 | 9.63 | 14 | 18.60 | 7.69 | −0.79 (−1.57; −0.02) |
| Pain elicited by thermal stimulus | |||||||
| Cooley, 1989 | 28 | 2.70 | 0.81 | 28 | 2.10 | 0.81 | 0.73 (0.19; 1.27) |
| Temperature at which patient report pain (thermal stimulus) | −0.50 (−1.84; 0.85) | ||||||
| Hansson, 1987 | 14 | 2.34 | 1.07 | 14 | 3.50 | 0.78 | −1.20 (−2.02; −0.39) |
| Muzzin, 1989 | 17 | 4.29 | 2.33 | 17 | 3.76 | 3.59 | 0.17 (−0.50; 0.84) |
|
| |||||||
|
6% monohydrogen monopotassium oxalate
| |||||||
| Pain elicited by tactile stimulus | |||||||
| Pereira, 2001 | 15 | 1.06 | 0.79 | 7 | 0.66 | 0.86 | 0.47 (−0.44; 1.38) |
| Pain elicited by evaporative stimulus | |||||||
| Pereira, 2001 | 16 | 0.46 | 0.74 | 8 | 0.55 | 1.13 | −0.10 (−0.95; 0.75) |
|
| |||||||
|
30% dipotassium oxalate
| |||||||
| Temperature at which patient report pain (thermal stimulus) | |||||||
| Muzzin, 1989 | 17 | 4.24 | 3.59 | 17 | 3.76 | 3.59 | 0.13 (−0.54; 0.80) |
|
| |||||||
|
6.8% ferric oxalate
| |||||||
| Pain elicited by evaporative stimulus | |||||||
| Gillam, 2004 | 13 | 5.04 | 3.04 | 13 | 5.65 | 2.89 | −0.20 (−0.97; 0.57) |
| Temperature at which patient report pain (thermal stimulus) | |||||||
| Gillam, 2004 | 13 | 7.41 | 7.67 | 13 | 10.55 | 3.60 | −0.51 (−1.29; 0.28) |
| Force at which patient report pain (tactile stimulus) 13 | |||||||
| Gillam, 2004 | 13 | −17.25 | 20.79 | 13 | −15.42 | 10.49 | −0.11 (−0.88; 0.66) |
|
| |||||||
|
Oxalate pre-polymarized resin
| |||||||
| Pain elicited by tactile stimulus | |||||||
| Morris, 1999 | 18 | 19.60 | 30.40 | 16 | 16.80 | 22.60 | 0.10 (−0.57; 0.78) |
| Pain elicited by evaporative stimulus | |||||||
| Morris, 1999 | 18 | 28.30 | 32.20 | 16 | 15.10 | 21.30 | 0.47 (−0.22; 1.15) |