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. Author manuscript; available in PMC: 2012 Mar 28.
Published in final edited form as: J Neurosci. 2011 Jul 20;31(29):10463–10473. doi: 10.1523/JNEUROSCI.1350-11.2011

Figure 2.

Figure 2

Inhibition mediated by GABAB-receptors does not significantly shape Purkinje cell response patterns.

A, Sample pseudocolor sagittal ΔFR maps of the same Purkinje cell with inhibition intact (left), with only GABAB receptors blocked (middle), and with both GABAB and GABAA receptors blocked (right). The baseline firing rates of this cell in the three conditions were 48, 48, and 53 spikes/s, respectively. Gray areas represent dendritic sites where glutamate photolysis directly targeted the recorded Purkinje cell. White pixels represent sites in which no data was obtained due to stimulation failures or noise.

B, Average vertically-collapsed profiles of Purkinje cell responses to glutamate photorelease in the granule cell layer with inhibition intact (open black triangles), with only GABAB receptors blocked (open burgundy triangles), and with both GABAB and GABAA receptors blocked (closed black triangles). The average change in firing rate from baseline from five cells is plotted as a function of lateral distance from the soma of the recorded Purkinje cell. Area plots showing the differences in change in firing rate between conditions are superimposed.