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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Cell Res. 2011 Oct 11;22(4):746–756. doi: 10.1038/cr.2011.162

Figure 5. Superposition of the RU-486-bound PPARγ to rosiglitazone-bound PPARγ and RU-486-bound GR LBD.

Figure 5

(A &B) Overlays of the PPARγ-RU486 structure (blue) with the PPARγ-rosiglitazone (gold) structure, where ligand RU-486 is in green and rosiglitazone is in purple. (C &D) Overlays of the PPARγ-RU486 structure (blue) with the GR-RU-486 structure (cyan), where ligand RU-486 is in green for PPARγ and the GR-bound RU-486 is in yellow. The dashed arrows indicate the positions of the dimethylaniline side chain of RU486 .