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Electrically active human pulmonary artery smooth muscle cells (PASMC). (a) Histogram showing the wide distribution of resting Em in human PASMC. Em was measured in the current clamp (I=0) mode. (b) Spontaneous action potentials recorded in human PASMC are abolished when external Ca2+ is removed. Electrical activity is restored upon return to normal physiological Ca2+ (1.8 mM)
