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. Author manuscript; available in PMC: 2011 Dec 21.
Published in final edited form as: Am J Cardiovasc Dis. 2011;1(1):92–100.

Figure 1.

Figure 1

Advanced remodeling with calcification, necrotic core and elastic fiber degradation of atherosclerotic plaques in ApoE null mice that express human S100A12 in the smooth muscle (a–c) compared to WT/ApoE littermate mice (d–f). Alizarin Red stain for calcium (a,d), H&E stain (b,e) and Verhoeff van Giessen stain for elastic fibers (c,f). L-lumen, FFN-fibrofatty nodule, *** osteoblast like cells. Modified and reproduced with permission from Hofmann Bowman et al [5].