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. Author manuscript; available in PMC: 2008 Mar 13.
Published in final edited form as: J Neurosci. 2007 Feb 21;27(8):1954–1963. doi: 10.1523/JNEUROSCI.2894-06.2007

Figure 7.

Figure 7

Blockade of glutamate receptors differentially affected early and later components of some sustained units. In two units, drug effects were analyzed for early (0–9 ms) and later (10–150 ms) response components. A. NBQX primarily blocked early spikes in this IC unit. BF: 57.9 kHz; MT: 39 dB SPL; Minimum latency: 8.1 ms. Rate-level function of entire response (0–150 ms, top), PSTHs (middle), and rate-level functions of early (0–9 ms) and later (10–150 ms) components (bottom) relative to beginning of response. B. CPP blocked later spikes more effectively in this unit (BF: 57.9 kHz; MT: 14 dB SPL; Minimum latency: 10.2 ms), although CPP substantially reduced early spikes at higher sound levels. Vertical dotted lines in PSTHs separate early and late spikes. Numbers at bottom right of each PSTH represent total spikes for 150 ms time window; numbers in windowed regions above PSTHs separately display spike counts for early and late excitation. Drug application times and currents: A. NBQX, 18 min., −80 nA; RECOVERY, 10 min. B CPP, 12 min., −40 nA; RECOVERY, 11 min. See Figure 2 for protocol.