Table 1. Intrinsic electrophysiological properties of striatal NPY interneurons.
All values are means ± SEM. Numbers in parentheses refer to the range of values. n refers to number of neurons from which the measurements were obtained. AP, action potential; RMP, resting membrane potential; AHP, afterhyperpolarizing; LTS, low threshold spike.
| Parameter | Input Resistance (MΩ) |
RMP (mV) |
AP Threshold (mV) |
AP Width 50% (ms) |
AP Amplitude (mV) |
AHP Amplitude (mV) |
AHP Duration (ms) |
Spontaneous Firing Rate (Hz) |
LTS |
Ih Ratio |
|---|---|---|---|---|---|---|---|---|---|---|
| NPY-PLTS (44) | 744 ± 51 (310 to 1702) | −63 ± 1(−79 to −51) | −45 ± 1 (−53 to −38) | 1.3 ± 0.05(0.75 to 2) | 74 ± 1.8 (56 to 108) | 17 ± 1 (9 to 25) | 134±11 | 6.4 + 0.5 (2 to 12) 30/44 | 35/44 | 1.1 ± 0.005 (1.01 to 1.4) 43/44 |
| NPY-NGF (19) | 142 ± 13* (74 to 260) | −88 ± 1* (−95 to −79) | −44 ± 1 (−48 to −39) | 1.25 ± 0.08 (0.74 to 1.9) | 80 ± 2 (64 to 101) | 26 ± 1* (20 to 32) | 140±5 | 0/19 | 0/19 | 1 ± 0 |
*
signifies p < 0.001,
#
signifies p < 0.05, Students 2-tailed t-test.