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. Author manuscript; available in PMC: 2012 Oct 21.
Published in final edited form as: J Neurosci. 2011 Nov 16;31(46):16814–16825. doi: 10.1523/JNEUROSCI.3064-11.2011

Figure 8.

Figure 8

Rotarod performance of wild-type and Hcn1−/− mice. 18 mice (5 wild-type and 13 Hcn1−/−) were tested for balance deficits using the rotarod apparatus. Mice were tested between 1.5 and 2 months of age. A, Time to fall during training on a stationary rod. Naïve wild-type mice showed little difficulty with this task, while Hcn1-deficient mice required multiple trials before demonstrating the ability to remain on the stationary rod. B, Time spent on the rotarod apparatus accelerating at 0.1 RPM/s from a starting speed of 2RPM. Hcn1-deficient mice fell significantly earlier than wild-type controls on each of the three trials. Trial 4 indicates a dark trial in which the lights were turned off in order to limit visual compensation. Statistically significant differences are marked with asterisks.