Table 4.

Ontology analysis of molecular and cellular components down-regulated at 3 days compared with 0 days.

Annotation	Gene Set	z-score*
Signaling pathways
Positive regulation of stress-activated protein kinase signaling pathway	20	4.12
JNK cascade	90	2.91
Stress-activated protein kinase signaling pathway	98	2.64
Negative regulation of transforming growth factor beta receptor signaling pathway	32	2.86
Regulation of stress-activated protein kinase Signaling pathway	66	2.58
Positive regulation of MAPKKK cascade	45	2.05
Cell metabolic process
Primary metabolic process	730	3.28
	5
Protein modification process	149	3.26
	8
mRNA processing	322	3.17
Protein amino acid dephosphorylation	132	3.17
Metabolic process	804	3.13
	9
Cellular macromolecule metabolic process	576	3.13
	3
Negative regulation of translation	29	3.11
DNA catabolic process	55	3.1
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	410	2.95
	3
Cellular activity regulations
Cellular metabolic process	715	2.8
	8
Protein ubiquitination	129	2.77
Cellular biopolymer catabolic process	691	2.31
Negative regulation of cell communication	233	2.25
Regulation of cell communication	927	2.02
Regulation of macromolecule biosynthetic process	264	2.01
	5
Regulation of kinase activity	339	2
Enzyme linked receptor protein signaling pathway	416	1.65

^*z-score, calculated in GeneScifter, detailed formula is presented in Supplemental Method.