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. Author manuscript; available in PMC: 2012 Jun 7.
Published in final edited form as: J Neurosci. 2011 Dec 7;31(49):18137–18148. doi: 10.1523/JNEUROSCI.3041-11.2011

Figure 5.

Figure 5

Parvalbumin deficit causes reduced response to stimuli. A1, A2, Spectrograms (time frequency) of network LFP, for baseline scenario (A1) and scenario with PV deficiency (F[PV] = 0 = 0.4, A2). In both cases, stimulus was presented at T = 2 s (arrow) and lasted for 40 ms. Stimulus rate was 400 Hz. B1, Spectral response averaged over time duration of stimulus presentation for baseline (black) versus the PV-deficient (red) models. B2, Spectral response averaged over time duration of 200 ms after stimulus cessation for baseline (black) versus PV-deficient (red) models. Stimulus rate was 400 Hz. C1, Magnitude of spectral power peak (time average over stimulus duration) versus F[PV] = 0 and relative (to the baseline stimulation of v0 = 150 Hz) increase in stimulation rate. C2, Firing rates of PY (black) and IN (red) model neurons during the 40 ms stimulus, in baseline (solid line) versus the F[PV] = 0 = 0.4 model (dashed line). D1, Magnitude of spectral power peak (time average over 200 ms after stimulus) versus F[PV] = 0 and relative (to the baseline stimulation of v0 = 150 Hz) increase in stimulation rate. D2, Firing rates of PY (black) and IN (red) model neurons in the time window of 200 ms after the stimulus, in baseline (solid line) versus the F[PV] = 0 = 0.4 model (dashed line).