Table 2.

Association of MITF E318K with melanoma-associated variables

	Australia				UK
Case set	Carrier frequency	Carrier counts (carrier/wild type)	OR vs Aus controls	95% CI	Carrier frequency	Carrier counts (carrier/wild type)	OR vs UK controls	95% CI
All cases	0.0165	34/2,025	2.33	1.21–4.70	0.0176	34/1,895	2.09	1.14–3.94
Age of onset <40 years	0.0139	14/996	1.95	0.86–4.42	0.0174	5/283	2.10	0.60–5.91
Family history of melanoma	0.0209	12/563	2.95	1.23–6.92	0.0273	3/107	3.36	0.62–11.77
Multiple primary melanomas	0.0296	8/262	4.22	1.52–10.91	0.0225	2/87	2.74	0.30–11.74
Multiple melanomas and family history	0.0571	6/99	8.37	2.58–23.80	0.0000	0/10	-	-

Aus, Australia.