Virus infectivity in SRECs following cell treatment with Vibrio cholerae sialidase. Cells were treated with sialidase for 3 h, washed and infected with 3 TCID50/cell (A), 1 TCID50/cell (B) or 0.3 TCID50/cell (B). Results shown are mean +/− SEM of three experiments performed in triplicate. Compared to untreated cells, each virus demonstrated significantly lower (p < 0.01) infectivity levels in SRECs treated with 0.001 U, 0.003 U, or 0.01 U of sialidase.