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PKA did not alter the ATP-induced ΔR-CFTR chloride channel currents. (A) Single-channel currents were induced by ATP application 2 min after patch excision. Subsequent addition of PKA did not alter the channel activity. (B) Expanded traces of the recording in A. (C) Summary of the measured Po with 2.75 mM ATP alone and with both 2.75 mM ATP and PKA (25 U/ml) (n = 6).
