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. Author manuscript; available in PMC: 2012 Mar 19.
Published in final edited form as: J Neurosci. 2007 Jul 25;27(30):7899–7910. doi: 10.1523/JNEUROSCI.1396-07.2007

Table 3.

Neuropathological analysis of brains from L-DOPA/TBZ trial mice

Group number Group name Number of mice Brain weight (g) Neuron counts (×106 cells) MSN cross-sectional area (μm2)
1 WT-Ctrl 9 (5F, 4M) 0.508 ± 0.025 1.264 ± 0.035 85.75 ± 2.33
2 WT-DOPA 7 (5F, 2M) 0.501 ± 0.020 1.225 ± 0.016 87.51 ± 1.98
3 WT- DOPA/TBZ 8 (5F, 3M) 0.501 ± 0.019 1.258 ± 0.020 91.34 ± 2.57
4 YAC-Ctrl 9 (4F, 5M) 0.432 ± 0.007 1.090 ± 0.020 71.99 ± 1.48
5 YAC-DOPA 8 (4F, 4M) 0.423 ± 0.008 1.014 ± 0.028 75.53 ± 1.16
6 YAC- DOPA/TBZ 7 (4F, 3M) 0.464 ± 0.010 1.182 ± 0.026 77.21 ± 1.15

The average brain weight, striatal neuronal counts, and striatal neuron cross-sectional area were measured in 11-month-old WT and YAC128 mice at the conclusion of the L-DOPA/TBZ trial. Several mice died during the behavioral stage of the trial and were not used in neuropathological analysis. The data are shown as mean ±SEM.