Table 1.
Numerical results (and percentages) from the regeneration screen and subsequent rescreens | |||
---|---|---|---|
Library | Initial screen | Rescreen |
Confirmed by dose- response analysis |
NINDS Custom Collection II | |||
Number of drugs evaluated | 1040 | 189 | 5 |
Number of putative enhancers* | 86 (8.3%) | 2 (0.2%) | 2 (0.2%) |
Number of putative inhibitors** | 103 (9.9%) | 3 (0.3%) | 0 |
BioMol FDA-approved I | |||
Number of drugs evaluated | 640 | 102 | 45 |
Number of putative enhancers* | 29 (4.5%) | 8 (1.3%) | 0 |
Number of putative inhibitors** | 73 (11.4%) | 37 (5.8%) | 6 (0.9%) |
Putative enhancers average scored ≥ 3.5
Putative inhibitors average scored ≤ 2.5