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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Antiviral Res. 2012 Mar 23;94(3):258–271. doi: 10.1016/j.antiviral.2012.03.005

Figure 7.

Figure 7

Quercetin decreases viral load in vivo. C57BL/6 mice were infected with RV1B or sham by the intranasal route. Two hours after RV infection, mice were orally gavaged with quercetin (0.2 mg/mouse) or 50% propylene glycol (PG) and then once a day up to 4 days. Mice were sacrificed and infectious viral load (A) was determined by measuring CCID50/ml. Positive strand vRNA (B) was determined by qPCR and negative strand vRNA (C) was detected by qPCR followed by agarose gel electrophoresis. A and B, data represent geomean and range of data from 2 independent experiments carried out in triplicate (†p≤0.05, different from mice infected with RV1B infected and treated with PG). C, PCR product from two representative animals from PG and quercetin group showing negative-strand vRNA and 18S RNA.