Table 3.
Axon Guidance Defects in fmi-1 and cdh-4 mutants
| % wild typea | L/R defects | Defasciculation | N | |
|---|---|---|---|---|
| GABAergic (DD and VD) | ||||
| wild type | 98 | 2% | 0% | 50 |
| fmi-1(ju43) | 12% | 48% | 50% | 70 |
| fmi-1(tm306) | 10% | 67% | 36% | 70 |
| fmi-1(tm306) lhIs9 | 24% | 27% | N/D | 76 |
| lhIs9 | 12% | 68% | N/D | 70 |
| fmi-1(tm306);FMI-1GFP (high) | 16% | 64% | N/D | 25 |
| cdh-4(lq83) | 15% | 30% | 29% | 79 |
| cdh-4(lq83);fmi-1(tm306) | 6% | 35% | 22% | 49 |
| L1 GABAergic (DD only) | ||||
| wild type | 98% | 0% | 2% | 100 |
| fmi-1(ju43) | 92% | 5% | 3% | 100 |
| Cholinergic (DA and DB) | ||||
| wild type | 90% | 8% | 2% | 60 |
| fmi-1(ju58) | 5% | 5% | 95% | 20 |
a
Percentage of animals without any L/Ror defasciculation events