Table 10.
Asymmetrical effects of cumulative life stress on the brain
| Original Region (MNI Coordinates) | Mean of original cluster (+/− standard deviation) | Mean of Inverted Cluster (+/− standard deviation) | Test of the difference between regions |
|---|---|---|---|
| Right Putamen (+28, +7, +0) | −0.136 (+/−0.132) | −0.092 (+/0.122) | F=3.675 p=.056 |
| Left Putamen (−21, +11, +10) | −0.161 (+/−0.123) | −0.149 (+/−0.127) | F=.259 p=.612 |
| Right Occipital Lobe (+30, −88, −13) | 0.076 (+/0.253) | 0.057 (+/0.224 | F=.191 p=.662 |
| Right Occipital Lobe (+9, −88, −4) | 0.017 (+/−0.236) | −0.158 (+/−0.264) | F=14.875 p<.001 |
| Left Occipital Lobe (−8, −96, −18) | 0.217 (+/−0.177) | 0.136 (+/−0.158) | F=7.087 p=.009 |
| Right Middle Temporal Gyrus (+52, −11, −12) | −0.102 (+/−0.218) | −0.127 (+/0.213) | F=.392 p=.553 |
| Left Middle Temporal Gyrus (−62, −17, −7) | −0.0071 (+/− 0.199) | −0.024 (+/−0.218) | F=.187 p=.667 |
| Right Parietal White Matter (+32, −27, +33) | −0.147 (+/−0.147) | −0.141 (+/−0.129) | F=.073 p=.788 |
| Right Middle Parietal Gyrus (+59, −42, +9) | −0.117 (+/−0.25) | −0.141 (+/−0.25) | F=.274 p=.602 |
| Right precuneus (+8, −58, +14) | 0.019 (+/− 0.21) | −0.039 (+/−0.189) | F=2.504 p=.116 |
| Right Cerebellum (+41, −67, −22) | −0.056 (+/−0.243) | −0.121 (+/−0.24) | F=2.154 p=.145 |
| Right Prefrontal White Matter (+18, +38, +1) | −0.08 (+/0.15) | −0.047 (+/0.156) | F=1.483 p=.226 |
| Right Frontal White Matter (+18, −12, +42) | −0.019 (+/−0.146) | −0.028 (+/−0.164) | F=.077 p=.782 |
| Left Frontal Pole (−20, +62, −9) | −0.193 (+/−0.266) | −0.0396 (+/−0.158) | F=14.854 P<.001 |
| Left Anterior Cingulate (−11, +45, +17) | −0.046 (+/−0.255) | −0.086 (+/−0.228) | F=.848 p=.359 |
The cluster in the ventral medial PFC (MNI coordinates: +0, +23, −24) was omitted from these analyses because it was located on the midline.