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. Author manuscript; available in PMC: 2012 Nov 2.
Published in final edited form as: J Neurosci. 2012 May 2;32(18):6081–6091. doi: 10.1523/JNEUROSCI.6519-11.2012

Figure 5. CCH-induced and DHPG-induced ADPs can occur without activation of the other receptor type.

Figure 5

(A) Individual responses to bursts of five action potentials in baseline condition (gray, t = 0 min in B) or after application (black, t = 15 min in B) of either 8 μM CCH or 2 μM DHPG. Experiments are performed in six different groups: control, 10 μM MPEP + 100 μM LY367385, and 10 μM Atropine in either CCH groups or DHPG groups. (B) Timecourses of the post-burst potential amplitudes following application of either CCH or DHPG beginning at t = 0 min. (C) Summary of the Δ post-burst potential (t = 15 min minus t = 0 min response) in each condition. Each symbol represents the amplitude of individual experiments. Red line and blue line show the average of control in CCH groups and DHPG groups, respectively. In CCH groups; control, n = 13; MPEP + LY367385, n = 11; Atropine, n = 9. In DHPG groups; control, n = 14; MPEP + LY367385, n = 9; Atropine, n = 12. One-way ANOVA, p < 0.0001; post-hoc tests vs. control: ** p < 0.001.