Figure 5. Decreased brain glucose uptake in R6/2 mice.
A. Representative 2DG autoradiographies, [pseudocolor images] comparing 6 week old WT and R6/2 mice, in basal conditions. ROIs are identified in the horizontal single hemisphere slices at two different ventro-dorsal levels as: PFC, PMC and St. The calibration bar represent higher signals as warmer colors. B. Mean normalized glucose utilization and SD in several ROIs as described above.
St= striatum, PMC=primary motor cortex, PFC=prefrontal cortex * denotes p value <0.05, and ** p value < 0.01