Table 1.
Biomarker Ratios among Splenectomized and Normal Control Subjects (medians) and in those according to the Indication for Splenectomy.
| Biomarker Median Ratio | Splenectomy | Controls | Overall p value |
Hypersplenism p value |
ASS p value |
|---|---|---|---|---|---|
| IL-1α:IL-10 | 28.8 | 9.5 | 0.004 | 0.034 | 0.038 |
| IL-1α:IL-1RA | 21.9 | 8.1 | 0.013 | 0.052 | 0.083 |
| IL-1α:Eotaxin | 3.2 | 1.6 | 0.003 | 0.064 | 0.021 |
| IL-1α:IL-6 | 114.6 | 34.4 | 0.005 | 0.161 | 0.005 |
| IL-1α:G-CSF | 1.5 | 0.8 | 0.021 | 0.093 | 0.161 |
| IL-1α:IL-9 | 109.5 | 41.5 | 0.029 | 0.329 | 0.121 |
| CXCL10:IL-7 | 498 | 220 | 0.038 | 0.024 | 0.955 |
| CXCL10:FGF-2 | 7.6 | 3.9 | 0.004 | 0.052 | 0.038 |
| CXCL10:PDGF-AA | 0.6 | 0.2 | 0.022 | 0.185 | 0.083 |
| CXCL10:PDGF-AA/AB | 0.1 | 0.06 | 0.009 | 0.077 | 0.105 |
| CXCL10:Flt-3 | 445 | 262 | 0.030 | 0.183 | 0.329 |
| CXCL10:EGF | 37.6 | 16.1 | 0.006 | 0.064 | 0.065 |
| IL-6:IL-5 | 0.3 | 1.1 | 0.012 | 0.152 | 0.041 |