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. Author manuscript; available in PMC: 2012 Dec 3.
Published in final edited form as: J Invest Dermatol. 2012 Jun 28;132(12):2735–2743. doi: 10.1038/jid.2012.205

Figure 2. Immunization with rLJM11 Protects Mice against Leishmania major-Infected Lutzomyia longipalpis Vector Challenge.

Figure 2

(a) Parasite load from lymph nodes (LN) or ears of rLJM11- or BSA-immunized mice two weeks post-sand fly challenge. Panel: cutaneous lesions at this time point. (b) ELISA measurements of IFN-γ, IL-10, and IL-4 from LN cells of BSA or rLJM11-immunized mice after stimulation with SLA or rLJM11. (c) Lesion thickness in animals immunized with rLJM11 (■) or BSA (●) following challenge with 10 infected sand flies. (d) Parasite load 5 weeks after infected sand fly challenge in the LN and ears of BSA or rLJM11- immunized mice. *, p < 0.05; **, p < 0.01; ***, p < 0.001. Cumulative data of two independent experiments are shown (n = 5).