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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Virus Res. 2012 May 19;167(2):247–258. doi: 10.1016/j.virusres.2012.05.006

Fig. 8. Swapping of Domain I between MHV and other CoV nsp15s.

Fig. 8

(A) Diagram showing the replacement of Domain I of SARS-CoV and TGEV nsp15 with the corresponding domain of MHV nsp15, and the resultant chimeric constructs. Only the nsp15 region of the EGFP fusion construct is shown. (B) Expression and detection of speckles for the chimeric constructs.