Lens 4-hydroxynonenal adducts and nitrotyrosine concentrations in control and diabetic rats maintained with or without cariporide treatment. C, control group; D, diabetic group; Ca, cariporide; 4-HNE, 4-hydroxynonenal. Mean ± SEM, n=6/group. *P<0.05 and **P<0.01 vs. the controls; #P<0.05 and ##P<0.01 vs. the untreated diabetic group.