Table 2.
ALDH genes and duplicated genes across species with respective chromosome (Chr) locations. Numbers in parentheses indicate NCBI Entrez gene ID (GI). Records in bold text denote duplications compared with the human genome. Z, the sex Chr in birds (ZW system); cM, centiMorgans. Letter designations in mouse gene locations indicate chromosomal regions
| Gene (by homology) | Primates
|
Rodents
|
Birds
|
Fish Zebrafish* | ||||
|---|---|---|---|---|---|---|---|---|
| Human | Orangutan | Cow | Rat | Mouse | Zebra finch | Chicken | ||
| ALDH1A1 | 9q21.13 (216) | 9 (100174688) | 8 (281615) | 1q51 (24188) | 19 12.0 cM (11668) | Z (100223406) | Z (395264) | |
|
| ||||||||
| ALDH1A2 | 15q21.3 (8854) | 15 (100171834) | 10 (535075) | 8q24 (116676) | 9 42.0 cM (19378) | 10 (751771) | 10 (395884) | 7 (116713) |
|
| ||||||||
| ALDH1A3 | 15q26.3 (220) | 15 (100452276) | 21 (507093) | 1q22 (266603) | 7 (56847) | 10 (100231202) | 10 (395389) | 7 (751785) |
|
| ||||||||
| 28 (534200) | ||||||||
|
| ||||||||
| ALDH1A7 | 1q51 (29651) | 19 20.0 cM (26358) | ||||||
|
| ||||||||
| ALDH1B1 | 9q11.1 (219) | 9 (100174654) | 8 (281618) | 5q22 (298079) | 4 B2 (72535) | |||
|
| ||||||||
| ALDH1L1 | 3q21.3 (10840) | 3 (100172380) | 3 (505677) | 4 (64392) | 6 (107747) | 6 (798292) | ||
|
| ||||||||
| ALDH1L2 | 12q23.3 (160428) | 12 (100459691) | 5 (516864) | 7q13 (299699) | 10 (216188) | 1A (100230131) | 1 (418078) | 4 (100333269) |
|
| ||||||||
| ALDH2 | 12q24.2 (217) | 12 (100171596) | 17 (508629) | 12q16 (29651) | 5 F-G1 (11669) | 15 (100217978) | 15 (416880) | 5 (393462) |
|
| ||||||||
| 5 (368239) | ||||||||
|
| ||||||||
| 5 (100332355) | ||||||||
|
| ||||||||
| ALDH3A1 | 17p11.2 (218) | 17 (100446485) | 19 (281617) | 10q22 (25375) | 11 34.25 cM (11670) | |||
|
| ||||||||
| ALDH3A2 | 17p11.2 (224) | 17 (100171557) | 19 (513967) | 10q22 (65183) | 11 34.3 cM (11671) | 19 (100230924) | 19 (417615) | 15 (323653) |
|
| ||||||||
| 19 (100226132) | 15 (100000026) | |||||||
|
| ||||||||
| 21 (100329417) | ||||||||
|
| ||||||||
| 21 (447920) | ||||||||
|
| ||||||||
| ALDH3B1 | 11q13 (221) | 11 (100450634) | 29 (511469) | 1q42 (309147) | 19 (67689) | 5 (100232483) | 5 (428813) | 5 (557008) |
|
| ||||||||
| 29 (508879) | 5 (100229547) | |||||||
|
| ||||||||
| ALDH3B2 | 11q13 (222) | 1q42 (688800) | 19 (621603) | |||||
|
| ||||||||
| 1q42 (688778) | 19 (73458) | |||||||
|
| ||||||||
| ALDH3D1 | 3 (282559) | |||||||
|
| ||||||||
| ALDH4A1 | 1p36 (8659) | 1 (10072770) | 2 (100126042) | 5q36 (641316) | 4 66.1 cM (212647) | 21 (100228902) | 21 (419467) | 11 (394133) |
|
| ||||||||
| ALDH5A1 | 6p22 (7915) | 6 (100458767) | 23 (532724) | 17p11 (291133) | 13 A3.1 (214579) | 2 (100222151) | 2 (420818) | 16 (565235) |
|
| ||||||||
| 16 (100330723) | ||||||||
|
| ||||||||
| ALDH6A1 | 14q24.3 (4329) | 14 (100171652) | 10 (327692) | 6q31 (81708) | 12 39.0 cM (104776) | 5 (100226750) | 5 (423345) | 17 (436647) |
|
| ||||||||
| ALDH7A1 | 5q31 (501) | 5 (100461726) | 7 (507477) | 18q12.1 (291450) | 18 29.0 cM (110695) | Z (100223716) | Z (426812) | 10 (334197) |
|
| ||||||||
| ALDH8A1 | 6q23.2 (64577) | 6 (100450228) | 9 (513537) | 1p12 (685750) | 10 (237320) | 3 (100222753) | 3 (421695) | 23 (447801) |
|
| ||||||||
| ALDH9A1 | 1q23.1 (223) | 1 (100173126) | 3 (537539) | 13q24 (64040) | 1 H2 (56752) | 8 (100225645) | 8 (424405) | 8 (100005587) |
|
| ||||||||
| 2 (399481) | ||||||||
|
| ||||||||
| 8 (100006238) | ||||||||
|
| ||||||||
| ALDH16A1 | 19q13.33 (126133) | 19 (100434496) | 18 (506329) | 1q22 (361571) | 7 (69748) | 3 (492710) | ||
|
| ||||||||
| ALDH18A1 | 10q24.3 (5832) | 10 (100173488) | 26 (514759) | 1q54 (361755) | 19 (56454) | 6 (423976) | 12 (557186) | |
|
| ||||||||
| 12 (100329417) | ||||||||
*
Zebrafish genes are named in accordance with nomenclature guidelines described at http://www.zfin.org and established by Mullins et al.15