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. Author manuscript; available in PMC: 2012 Dec 20.
Published in final edited form as: J Neurosci. 2012 Jun 20;32(25):8475–8479. doi: 10.1523/JNEUROSCI.5333-11.2012

Figure 1.

Figure 1

CB1R regulated the activity of periglomerular cells. A, B. Original recordings illustrate that CB1R agonist WIN reduced the firing rate of an sPG cell. CB1R antagonist AM251 increased spiking of an sPG cell. Recordings for WIN and AM251 are from the same sPG cell. C Anandamide reduced firing and hyperpolarized membrane potential in an sPG cell. D Summary of cannabinoid effects on sPG cell activity in absence and presence of synaptic blockers. E. Original recording illustrates depolarization of an nPG cell following bath application of AM251. sEPSPs were abolished following bath application of synaptic blockers (syn. blo.).