Table 1.
Structures and IC50 Values for 3,4-HOPTO Analogue Hits
| Compound | R | IC50 (μM) |
|---|---|---|
| 8a |
|
3.34 ± 0.03 |
| 8b |
|
2.73 ± 0.03 |
| 8c |
|
3.58 ± 0.05 |
| 8d |
|
4.65 ± 0.17 |
| 8e |
|
6.72 ± 0.01 |
| 8f |
|
8.58 ± 0.01 |
| 8g |
|
5.27 ± 0.01 |
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