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Influence of SULT1A1 3′-UTr haplotypes on fulvestrant (A) and β-naphthol (B) sulfation. Enzymatic activity was determined either colorimetrically (for β-naphthol) or by Lc-Ms/Ms. haplotype–phenotype relationships were assessed by analysis of variance with phenotype as the dependent variable.
Abbreviation: Lc-Ms/Ms, liquid chromatography–mass spectrometry/tandem mass spectrometry.
