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. Author manuscript; available in PMC: 2013 Mar 12.
Published in final edited form as: J Neurosci. 2012 Sep 12;32(37):12797–12807. doi: 10.1523/JNEUROSCI.0118-12.2012

Figure 1.

Figure 1

Prolonged Atoh7LacZ expression in retinas following diphtheria toxin ablation of RGCs in mice with one intact Atoh7 allele. A, C, E. LacZ histochemical staining shows that in Atoh7LacZ/+ retinas, LacZ-positive cells are detected at the retinal margins until P8. B, D, F. Cryosections of Atoh7LacZ/+;Pou4F2dta/+;Six3-Cre retinas following RGC ablation show increased numbers of Atoh7LacZ positive cells in the retinal margin at each corresponding stage. Cells positive for LacZ are still detectable at P14 despite the presence of the same wildtype Atoh7 allele as in the controls. Scale bar = 100 μm.