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. Author manuscript; available in PMC: 2013 Mar 12.
Published in final edited form as: J Neurosci. 2012 Sep 12;32(37):12841–12847. doi: 10.1523/JNEUROSCI.2784-12.2012

Figure 2. Reduced mGluR5 expression in Mecp2S421A;S424A/y hippcoampal neurons.

Figure 2

A. Relative mRNA level of Grm5, Grm1, Gria1, Gria2 and Mecp2 in cultured hippocampal neurons (18 DIV) derived from Mecp2S421A;S424A/y mice and their wild type littermates. (n=8 in each genotype) B and C. Western blot and quantification showing relative protein level of mGluR5 and mGluR1 in cultured hippocampal neurons (18 DIV) derived from Mecp2S421A;S424A/y mice and their wild type littermates ( n=15 in each genotype). The bar graph shows the mean ± s.e.m * p<0.05. ** p<0.01