Table 1.

Summary of the parameter values used in our simulations

Da	0.1 μm2/s	diffusion of the active form A in the membrane
Db	10 μm2/s	diffusion of the inactive form B in the cytoplasm (deterministic system only)
k0	0.067 s−1	rate of background activation
γ	1 s−1	maximal rate of auto-activation of A
δ	1 s−1	rate of background inactivation
K	1 μM	concentration of A resulting in half-maximal rate of auto-activation (deterministic system)
KN	…	as constant K but rescaled depending on current volume of the system (KN ∝ NAH LW·K, where NA is Avogadro’s number)
ks	10 s−1	rate of activation due to transient pulse
L	10 μm	length of the domain
N	50	number of membrane lattice points