Table 3.
Grey matter areas associated with Personality.
| Contrast | Localization (neuroanatomical region and Brodmann’s area) | Cluster size (voxels) | Peak-voxel t-statistic (Z value) | Significance level (after FWE- correction_ | βcoefficient (GM RAVENS voxel value)/(NEO Factor T-score) | Peak- voxel(s) MNI coordinates |
|---|---|---|---|---|---|---|
| Positive linear correlation with N | (R) LG, BA 17 | 3604 | 4.78 | Cluster-level: p < 0.001 | 0.80 | 14, −66, 2 |
| (R) FG, BA 37/20 | 3131 | 4.40 | Cluster-level: p < 0.001 | 1.40 | 53, −58, −24 | |
| (R) MOG, BA 18 | 439 | 4.38 | Cluster-level: p = 0.035 | 0.14 | 29, −98, 1 | |
| (R) precentral gyrus, BA 4 | 1874 | 3.57 | Cluster-level: p < 0.001 | 1.90 | 36, −27, 66 | |
| (R) CG, BA 18 | 700 | 3.51 | Cluster-level: p = 0.002 | 2.08 | 10, −82, 16 | |
| Negative linear correlation with N | (R) IOFG, BA 47 (lateral OFC) | 1036 | 5.23 | Cluster-level: p < 0.001 | −0.62 | 42, 38, −23 |
| (R) Rolandic opperculum, BA 22 | 3372 | 4.83 | Cluster-level: p < 0.001 | −0.75 | 70, −7, 12 | |
| (R) MFG, BA 46 | 2863 | 4.55 | Cluster-level: p < 0.001 | −1.30 | 52, 46, 15 | |
| (R) PHG, BA 28 | 898 | 4.27 | Cluster-level: p < 0.001 | −1.30 | 20, 2, −30 | |
| (R) MTG, BA 21 | 1087 | 3.89 | Cluster-level: p < 0.001 | −2.06 | 59, 1, −26 | |
| Positive linear correlation with E | (L) STG, BA 22 extending into the (L) MTG, BA 21; ITG, BA20; PHG, BA 36 | 21333 | 5.60 | Peak-level: p =0.008; Cluster-level: p < 0.001 | 1.66 | −50, −8, −7 |
| (R) MFG, BA 44/46 | 6646 | 5.45 | Peak-level: p =0.018; Cluster-level: p < 0.001 | 1.18 | 34, 22, 34 | |
| (L) aCG, BA 32 | 13199 | 5.26 | Peak-level: p =0.044; Cluster-level: p < 0.001 | 1.86 | −6, 42, 15 | |
| (L) MFG, BA 46 | 7280 | 4.95 | Cluster-level: p < 0.001 | 1.72 | −26, 38, 26 | |
| (L) SMG, BA 3 | 2171 | 4.44 | Cluster-level: p < 0.001 | 1.69 | −60, −20, 42 | |
| (L) IOG, BA 19 | 622 | 4.36 | Cluster-level: p =0.004 | 0.75 | −53, −74, −7 | |
| (L) STG, BA 22 | 1029 | 3.95 | Cluster-level: p < 0.001 | 1.50 | −54, −26, 6 | |
| (L) SFG, BA 6 | 736 | 3.80 | Cluster-level: p =0.001 | 1.37 | −25, −8, 60 | |
| (R) insula | 638 | 3.80 | Cluster-level: p =0.004 | 1.48 | 38, 4, 1 | |
| Negative linear correlation with E | (R) PHG, BA 35 | 892 | 5.03 | Cluster-level: p < 0.001 | −0.51 | 24, −8, −32 |
| (L) IOG, BA 18 | 1914 | 5.02 | Cluster-level: p < 0.001 | −0.78 | −22, −101, −12 | |
| (L) SPL, BA 7 | 652 | 4.04 | Cluster-level: p =0.003 | −0.58 | −39, −63, 58 | |
| Positive linear correlation with O | (R) SFG, BA 10 (frontopolar cortex) | 5552 | 5.73 | Peak-level: p =0.004; Cluster-level: p < 0.001 | 0.75 | 16, 64, 22 |
| (L) thalamus | 1172 | 3.59 | Cluster-level: p < 0.001 | 2.55 | −11, −14, 17 | |
| Negative linear correlation with O | (R) SOFG, BA 11 (medial OFC) | 2758 | 6.34 | Peak-level: p < 0.001; Cluster-level: p < 0.001 | −0.72 | 24, 33, −13 |
| (L) MFG, BA 47 | 655 | 5.64 | Peak-level: p =0.007; Cluster-level: p =0.003 | −0.16 | −54, 43, −4 | |
| (R) FG, BA 36 | 4917 | 5.49 | Peak-level: p =0.014; Cluster-level: p < 0.001 | −0.83 | 19, 8, −44 | |
| (L) STG (fronto-insular cortex) | 3493 | 5.00 | Cluster-level: p < 0.001 | −1.88 | −41, −10, −9 | |
| (R) SFG, BA 6 | 1535 | 4.88 | Cluster-level: p < 0.001 | −0.86 | 24, −5, 70 | |
| (R) RG, BA 11 (medial OFC) | 4863 | 4.86 | Cluster-level: p < 0.001 | −1.41 | 8, 52, −18 | |
| (L) postcentral gyrus, BA 5 | 3469 | 4.84 | Cluster-level: p < 0.001 | −0.65 | −20, −46, 76 | |
| (R) precuneus, BA 7 | 1432 | 4.35 | Cluster-level: p < 0.001 | −1.12 | 3, −48, 39 | |
| (L) FG, BA 20 | 895 | 4.08 | Cluster-level: p < 0.001 | −1.49 | −36, −17, −36 | |
| (L) IPG, BA 40 | 1208 | 3.89 | Cluster-level: p < 0.001 | −1.59 | −48, −47, 42 | |
| (L) SMA, BA 6 | 789 | 3.80 | Cluster-level: p =0.001 | −1.17 | −3, 9, 60 | |
| Positive linear correlation with A | (R) IOFG, BA 47 (lateral OFC) | 1512 | 5.23 | Peak-level: p =0.050; Cluster-level: p < 0.001 | 0.57 | 31, 33, −25 |
| (R) MOFG, BA 46 (lateral OFC) | 5476 | 4.59 | Cluster-level: p < 0.001 | 1.36 | 45, 56, −2 | |
| (R) MTP, BA 20 | 1375 | 4.31 | Cluster-level: p < 0.001 | 1.63 | 46, 15, −42 | |
| (L) SPG, BA 7 | 917 | 3.78 | Cluster-level: p < 0.001 | 1.08 | −17, −57, 72 | |
| Negative linear correlation with A | (B) SMFG, BA 8 | 12987 | 5.75 | Peak-level: p =0.004; Cluster-level: p < 0.001 | −1.15 | −11, 36, 58 and 4, 40, 53 |
| (L) PHG, BA 28/36 | 2023 | 5.46 | Peak-level: p =0.017; Cluster-level: p < 0.001 | −1.22 | −16, −7, −28 | |
| (L) MFG, BA 46 | 1604 | 5.31 | Peak-level: p =0.035; Cluster-level: p < 0.001 | −0.90 | −44, 54, 18 | |
| (L) STG, BA 22 | 6105 | 5.26 | Peak-level: p =0.044; Cluster-level: p < 0.001 | −2.25 | −55, −23, 3 | |
| (L) SMFG, BA 32 | 698 | 4.05 | Cluster-level: p =0.002 | −0.92 | −6, 31, 36 | |
| (L) PHG, BA 37 | 992 | 3.90 | Cluster-level: p < 0.001 | −1.78 | −23, −36, −6 | |
| (R) calcarine gyrus, BA 17 | 2003 | 3.75 | Cluster-level: p < 0.001 | −1.96 | 15, −57, 10 | |
| Positive linear correlation with C | (B) SFG, BA 8; (R) > (L) | 17801 | 6.42 | Peak-level: p < 0.001; Cluster-level: p < 0.001 | 1.30 | 9, 45, 54 and −9, 49, 52 |
| (R) postcentral gyrus, BA 3 | 4159 | 5.34 | Peak-level: p =0.031; Cluster-level: p < 0.001 | 1.77 | 62, −13, 44 | |
| (L) precuneus, BA 5 | 6715 | 5.24 | Peak-level: p =0.048; Cluster-level: p < 0.001 | 1.79 | −13, −57, 65 | |
| (R) precentral gyrus, BA 6 | 2003 | 5.23 | Peak-level: p =0.049; Cluster-level: p < 0.001 | 0.87 | 38, −9, 67 | |
| (L) FG, BA 19 | 1896 | 4.84 | Cluster-level: p < 0.001 | 1.76 | −41, −64, −17 | |
| (L) caudate nucleus | 2814 | 4.67 | Cluster-level: p < 0.001 | 1.33 | −6, 7, 13 | |
| (R) SFG, BA 8 | 3835 | 4.63 | Cluster-level: p < 0.001 | 1.46 | 30, 9, 63 | |
| (L) SFG, BA 6 | 3646 | 4.61 | Cluster-level: p < 0.001 | 1.10 | −25, 3, 71 | |
| (L) aCG, BA 32 | 2858 | 4.52 | Cluster-level: p < 0.001 | 1.51 | −10, 42, 18 | |
| (R) STG, BA 22 and (R) IFG, pars opercularis, BA 44 | 5928 | 4.31 | Cluster-level: p < 0.001 | 1.96 | 59, −9, 10 and 56, 14, 12 | |
| (L) LG, BA 18 | 797 | 3.88 | Cluster-level: p =0.001 | 1.29 | −15, −64, −8 | |
| (L) hippocampus | 1814 | 3.75 | Cluster-level: p < 0.001 | 1.56 | −22, −37, 6 | |
| Negative linear correlation with C | (R) MTP, BA 38 | 3560 | 6.11 | Peak-level: p =0.001; Cluster-level: p < 0.001 | −0.21 | 20, 16, −36 |
| (L) STG, BA 21 | 736 | 5.46 | Peak-level: p =0.017; Cluster-level: p =0.003 | −0.26 | −64, −3, 1 | |
| (B) SMFG, BA 10 (frontopolar cortex) | 14345 | 5.28 | Peak-level: p =0.041; Cluster-level: p < 0.001 | −0.37 | 12, 69, 10 and −7, 72, 4 | |
| (L) SPL, BA 7 | 1782 | 5.18 | Cluster-level: p < 0.001 | −0.44 | −37, −66, 60 | |
| (L) CG, BA 17 | 4795 | 4.67 | Cluster-level: p < 0.001 | −0.54 | −2, −101, 11 | |
| (R) postcentral gyrus, BA 4 | 3843 | 4.61 | Cluster-level: p < 0.001 | −1.01 | 34, −34, 72 | |
| (R) IOFG, BA 11 (medial OFC) | 1289 | 4.26 | Cluster-level: p < 0.001 | −0.98 | 16, 39, −9 |
(R) = right; (L) = left; (B) = bilateral; IFG = inferior frontal gyrus; MFG = middle frontal gyrus; SFG = superior frontal gyrus; SMFG = superior medial frontal gyrus; SMA = supplemental motor area; IOFG = inferior orbital frontal gyrus; MOFG = middle orbital frontal gyrus; SOFG = superior orbital frontal gyrus; RG = rectal gyrus; ITG = inferior temporal gyrus; MTG = middle temporal gyrus; STG = superior temporal gyrus; MTP = middle temporal pole; aCG = anterior cingulate gyrus; PHG = parahippocampal gyrus; IPG = inferior parietal gyrus; SPL= superior parietal lobule; SMG = supramarginal gyrus; LG = lingual gyrus; FG = Fusiform gyrus; CG = calcarine gyrus; MOG = middle occipital gyrus; IOG= inferior occipital gyrus; MNI= Montreal Neurological Institute; NS = non-significant (association).